Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429746 | 0.85 | CYP2D6 (0.43) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL714416 | 0.85 | CYP2D6 (0.43) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL817869 | 0.85 | CYP2D6 (0.43) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL19548837 | 0.84 | MAOB (0.39) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL16059015 | 0.84 | MAOB (0.39) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL17499062 | 0.84 | MAOB (0.39) | LMNAALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL6507499 | 0.83 | LMNA (0.49) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL6137275 | 0.78 | CYP2D6 (0.42) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL6137281 | 0.78 | CYP2D6 (0.42) | CYP2D6LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL9794052 | 0.78 | CYP2D6 (0.42) | CYP2D6LMNAMAOAPTGS1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | CHRM3, CHRNB3, ADRB3 | CYP2D6 2316/4885LMNA 1138/4885MAOA 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.