⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269823 | 0.85 | — | — | |
| SCHEMBL4388330 | 0.79 | — | — | |
| SCHEMBL7152933 | 0.77 | ALOX15 (0.48) | — | |
| SCHEMBL1926899 | 0.73 | — | — | |
| SCHEMBL25057 | 0.71 | — | — | |
| SCHEMBL4331044 | 0.71 | — | — | |
| SCHEMBL2222863 | 0.71 | — | — | |
| SCHEMBL10431804 | 0.71 | — | — | |
| SCHEMBL18925257 | 0.71 | — | — | |
| SCHEMBL1469539 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030011-B2 | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | VTV THERAPEUTICS LLC (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2536285-B1 | SUBSTITUTED FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | VTV THERAPEUTICS LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-8759535-B2 | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof | HIGH POINT PHARMACEUTICALS, LLC (US) | 2014-06-24 | — | — | US | disclosed |
| WO-2007056279-A2 | PHOSPHOLIPASE INHIBITORS, INCLUDING MULTI-VALENT PHOSPHOLIPASE INHIBITORS, AND USE THEREOF, INCLUDING AS LUMEN-LOCALIZED PHOSPHOLIPASE INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056275-A2 | INDOLE COMPOUNDS HAVING C4-AMIDE SUBSTITUENTS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056281-A2 | MULTIVALENT INDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056184-A2 | AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| US-6864268-B2 | β3 adrenergic receptor agonists | PFIZER INC. (US) | 2005-03-08 | — | — | US | disclosed |
| EP-1485379-A1 | BETA 3-ADRENERGIC RECEPTOR AGONISTS | Pfizer Products Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040063987-A1 | Method for producing alkoxymalononitriles | BARTEK JOHANNES (CH) | 2004-04-01 | — | — | US | disclosed |
| US-6673957-B2 | DEHYDRATION OF ALKOXY MALONIC ACID DIAMIDES | LONZA AG (CH) | 2004-01-06 | — | — | US | disclosed |
| US-20030212063-A1 | beta3 adrenergic receptor agonists | PFIZER INC. | 2003-11-13 | — | — | US | disclosed |
| WO-2003072572-A1 | BETA3-ADRENERGIC RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| US-20030144538-A1 | Method for producing alkoxy malonic acid dinitriles | LONZA AG (CH) | 2003-07-31 | — | — | US | disclosed |
| EP-1254105-A1 | METHOD FOR PRODUCING ALKOXY MALONIC ACID DINITRILES | Lonza AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058857-A1 | METHOD FOR PRODUCING ALKOXY MALONIC ACID DINITRILES | LONZA AG (CH) | 2001-08-16 | — | — | WO | disclosed |
| EP-0112280-B1 | 2-ARYL-4,6-DIHALOGEN PYRIMIDINES AS ANTIDOTES FOR PROTECTING CULTIVATED PLANTS BEFORE PHYTOTOXIC DAMAGE CAUSED BY A HERBICIDE | CIBA-GEIGY AG (CH) | 1990-08-29 | — | — | EP | disclosed |
| US-4648896-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0112280-A2 | 2-Aryl-4,6-dihalogen pyrimidines as antidotes for protecting cultivated plants before phytotoxic damage caused by a herbicide | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| US-4061644-A | FROM A FURAN AND AMMONIA | CIBA-GEIGY CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |