Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227738 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7648281 | 0.86 | PDE4B (0.32) | CYP1A2CYP2A6MAPTPOLB | |
| SCHEMBL4744273 | 0.82 | CYP3A4 (0.31) | — | |
| SCHEMBL20524986 | 0.82 | CYP2A6 (0.32) | CYP2A6ALDH1A1 | |
| SCHEMBL357540 | 0.82 | CYP2A6 (0.45) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9558600 | 0.80 | KMT2A (0.32) | MAPTNPC1RAB9A | |
| SCHEMBL2214680 | 0.79 | CYP1A2 (0.31) | CYP1A2CYP2A6 | |
| SCHEMBL6945091 | 0.79 | PTPN1 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL2502936 | 0.79 | PTPN1 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL8691514 | 0.79 | HPRT1 (0.45) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4397 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946067-A | Method for realizing deuteration methylation of nucleophile | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117886987-A | Perfluorosulfonic acid ion copolymer and preparation method and application thereof | 复旦大学 | 2024-04-16 | — | — | CN | claimed |
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | DONGGUAN STEPHEN CATALYST CO., LTD. (CN) | 2023-10-17 | — | — | US | claimed |
| CN-116874438-A | One-pot method for preparing polysubstituted 1,2, 3-triazole compound | 大连理工大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114702429-B | Method for constructing 3-alkyl indole compounds by olefin difunctional | 南昌航空大学 | 2023-06-02 | — | — | CN | claimed |
| US-20230115208-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF TUBERCULOSIS | QURETECH BIO AB (SE) | 2023-04-13 | — | — | US | claimed |
| CN-115850329-A | Cycloterpyriaryl phosphines, their preparation and use | 东莞市均成高新材料有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113621236-B | High-performance composite dielectric elastomer and preparation method and application thereof | 北京化工大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115716849-A | Synthetic method of aryl phosphorus compound | 海南大学 | 2023-02-28 | — | — | CN | claimed |
| CN-110818611-B | Indolone compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-01-24 | — | — | CN | claimed |
| US-4442111-A | Antithrombotic sulfimino and sulfoximino indolinones-2 | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-04-10 | — | — | US | claimed |
| EP-0071150-A1 | Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1983-02-09 | — | — | EP | claimed |
| EP-0025190-A2 | Chromogenic compounds and their use as enzymatic substrates | BEHRINGWERKE Aktiengesellschaft (DE) | 1981-03-18 | — | — | EP | claimed |
| US-4247454-A | Novel chromogenic thrombin substrates | AB KABI (SE) | 1981-01-27 | — | — | US | claimed |
| US-4214049-A | SPECTROPHOTOMETRIC ANALYSIS OF HYDROLYSIS PRODUCTS | AB KABI (SE) | 1980-07-22 | — | — | US | claimed |
| US-4169015-A | PHENYLALANINE OR TYROSINE-AZEIDINE CARBOXYLIC ACID, PROLINE OR PIPECOLINIC ACID-ARGININE-CHROMOPHORE, SPECTROPHOTOMETRIC ANALYSIS OF ENZYMATIC HYDROLYSIS | AB KABI (SE) | 1979-09-25 | — | — | US | claimed |
| US-4162941-A | CONTACTING WITH A PEPTIDE SUBSTRATE AND MEASURING THE ENZYMATIC HYDROLYSIS | AB KABI (SE) | 1979-07-31 | — | — | US | claimed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | claimed |
| US-4137225-A | SPECIFIC FOR SERINE PROTEASE, ENANTIOMORPHS | AB KABI (SE) | 1979-01-30 | — | — | US | claimed |
| US-4028318-A | FOR SERINE PROTEASES | A B KABI (SW) | 1977-06-07 | — | — | US | claimed |