Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 3/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64917 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7648281 | 0.86 | PDE4B (0.32) | CYP1A2CYP2A6MAPTPOLB | |
| SCHEMBL4744273 | 0.82 | CYP3A4 (0.31) | — | |
| SCHEMBL20524986 | 0.82 | CYP2A6 (0.32) | CYP2A6ALDH1A1 | |
| SCHEMBL357540 | 0.82 | CYP2A6 (0.45) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9558600 | 0.80 | KMT2A (0.32) | MAPTNPC1RAB9A | |
| SCHEMBL2214680 | 0.79 | CYP1A2 (0.31) | CYP1A2CYP2A6 | |
| SCHEMBL6945091 | 0.79 | PTPN1 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL2502936 | 0.79 | PTPN1 (0.33) | CYP1A2CYP2A6 | |
| SCHEMBL8691514 | 0.79 | HPRT1 (0.45) | CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186660-B2 | Internal electron donor compound for preparing α-olefin polymerization catalyst component | YINGKOU XIANGYANG CATALYST CO., LTD. | 2021-11-30 | — | — | US | disclosed |
| US-20190218317-A1 | INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT | YINGKOU XIANGYANG CATALYST CO LTD (CN) | 2019-07-18 | — | — | US | disclosed |
| EP-1412336-A4 | PEPTOID COMPOUNDS | UNIV WOLLONGONG (AU) | 2007-08-29 | — | — | EP | disclosed |
| US-6855657-B2 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION | 2004-04-08 | — | — | US | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | BCKDK, PDK3, HCK | CYP1A2 1070/4885CYP2A6 1744/4885MAPT 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.