SCHEMBL357540

SCHEMBL357540

COc1[c]c2cc3ccccc3cc2cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.45
CYP1A2 P05177 1/20 0.45
NQO1 P15559 1/20 0.39
MAPT P10636 2/20 0.37
NQO2 P16083 2/20 0.36
CDK5 Q00535 1/20 0.36
CDK5R1 Q15078 1/20 0.36
TDP1 Q9NUW8 3/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5227738 0.82 CYP1A2 (0.40) CYP2A6CYP1A2NQO1MAPTNQO2
SCHEMBL64917 0.82 CYP1A2 (0.40) CYP2A6CYP1A2NQO1MAPTNQO2
SCHEMBL11660325 0.81 CA1 (0.35) CYP2A6CYP1A2MAPTTDP1ALDH1A1
SCHEMBL1127483 0.80 MAPK1 (0.38) CYP2A6CYP1A2NQO1MAPTTDP1
SCHEMBL328940 0.79 LTA4H (0.39) CYP2A6CYP1A2MAPTTDP1ALDH1A1
SCHEMBL11361135 0.78 CYP2A6 (0.47) CYP2A6CYP1A2NQO2ALDH1A1KDM4E
SCHEMBL1389303 0.78 GPBAR1 (0.40) CYP2A6CYP1A2MAPTTDP1TUBB4A
SCHEMBL4722150 0.78 RAB9A (0.41) CYP2A6CYP1A2MAPTTDP1ALDH1A1
SCHEMBL5144913 0.77 CYP2A6 (0.50) CYP2A6CYP1A2NQO1KDM4ECYP3A4
SCHEMBL16593579 0.77 GPR84 (0.32) TDP1ALDH1A1HSD17B10CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296738-B2 Organic electroluminescent material, the process for preparing the same and OLED device using the same EVERDISPLAY OPTRONICS (SHANGHAI) LIMITED (CN) 2016-03-29 US claimed
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME EVERDISPLAY OPTRONICS (SHANGHAI) CO., LTD. (CN) 2015-07-23 US claimed
WO-2010107784-A1 METHODS FOR ACTIVATION CONTROL OF PHOTOPOLYMERIZATION FOR HOLOGRAPHIC DATA STORAGE USING AT LEAST TWO WAVELENGTHS STX APRILIS, INC. (US) 2010-09-23 WO claimed
CN-118160125-A Electrolyte, sodium ion secondary battery, battery module, battery pack, and electricity using device 宁德时代新能源科技股份有限公司 2024-06-07 CN disclosed
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
WO-2023245331-A1 ELECTROLYTE, SODIUM ION SECONDARY BATTERY, BATTERY MODULE, BATTERY PACK, AND ELECTRIC APPARATUS 宁德时代新能源科技股份有限公司 2023-12-28 WO disclosed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-114424122-A Hard mask composition, hard mask layer and pattern forming method 三星SDI株式会社 2022-04-29 CN disclosed
US-20220069354-A1 SULFUR-BASED ELECTROLYTE SOLUTION FOR MAGNESIUM CELL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2022-03-03 US disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
WO-2006100591-A1 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-09-28 WO disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed
US-20050182224-A1 Acrylic copolymer KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2005-08-18 US disclosed
US-5817670-A RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-10-06 US disclosed
EP-0779292-A1 NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-06-18 EP disclosed
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
EP-0206251-A1 Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME OCIAD1, OCIAD2, OR10J3 CYP2A6 3575/4885CYP1A2 638/4885NQO1 338/4885
US-20220069354-A1 SULFUR-BASED ELECTROLYTE SOLUTION FOR MAGNESIUM CELL SLC26A3, PRDX4, PRDX2 CYP2A6 1852/4885CYP1A2 3884/4885NQO1 3122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.