Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40718 | 0.95 | THRB (0.67) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Carbon Monoxide SCHEMBL10707595 | 0.90 | THRB (0.61) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| SCHEMBL31453304 | 0.89 | HCAR2 (0.59) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| SCHEMBL149640 | 0.89 | THRB (0.59) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Benzoic Acid SCHEMBL11648503 | 0.87 | THRB (0.58) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Ethylene Glycol SCHEMBL1087639 | 0.87 | THRB (0.58) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Acrylic Acid Methyl Ester SCHEMBL28871054 | 0.87 | THRB (0.58) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| SCHEMBL9164139 | 0.87 | TSHR (0.63) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Biphenyl SCHEMBL14674230 | 0.86 | THRB (0.65) | THRBHCAR2AKR1B10AKR1B1TSHR | |
| Methacrylic Acid SCHEMBL7262507 | 0.86 | THRB (0.56) | THRBHCAR2AKR1B10AKR1B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852820-B2 | Method for preparing acrylic copolymer materials suitable for ophthalmic devices | NIDEK CO., LTD. (JP) | 2005-02-08 | — | — | US | disclosed |
| EP-1035142-A1 | Acrylic copolymer materials suitable for ophthalmic devices | Nidek Co., Ltd. (JP) | 2000-09-13 | — | — | EP | disclosed |