SCHEMBL649220

SCHEMBL649220

COc1ccc2c(C3COC(CCCNC(=O)OCC(N)=O)OC3)cccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACACB O00763 7/20 0.61
MTNR1A P48039 9/20 0.39
MTNR1B P49286 3/20 0.39
NQO2 P16083 1/20 0.39
ACACA Q13085 3/20 0.37
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649521 1.00 ACACB (0.61) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL649221 1.00 ACACB (0.61) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL649561 0.93 ACACB (0.52) ACACBMTNR1AMTNR1BNQO2
SCHEMBL649560 0.93 ACACB (0.52) ACACBMTNR1AMTNR1BNQO2
SCHEMBL648433 0.92 ACACB (0.61) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL648434 0.92 ACACB (0.61) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL649910 0.91 ACACB (0.60) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL649444 0.91 ACACB (0.60) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL650375 0.90 ACACB (0.59) ACACBMTNR1AMTNR1BNQO2ACACA
SCHEMBL649154 0.90 ACACB (0.59) ACACBMTNR1AMTNR1BNQO2ACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US claimed
EP-3879295-B1 CELLULAR POSITIONING BASED VERIFICATION OF AN ESTIMATED VEHICLE POSITION MAGNA ELECTRONICS SWEDEN AB (SE) 2025-06-25 EP claimed
EP-4315966-A1 METHODS FOR IMPROVED FEDERATED MACHINE LEARNING IN WIRELESS NETWORKS Telefonaktiebolaget LM Ericsson (publ) (SE) 2024-02-07 EP claimed
WO-2022199824-A1 METHODS FOR IMPROVED FEDERATED MACHINE LEARNING IN WIRELESS NETWORKS TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) 2022-09-29 WO claimed
EP-2545914-A1 2-amino-2-oxoethyl trans-3-[5-(6-methoxy-naphtalen-1-yl)-1,3-dioxan-2-yl]propyl-carbamate for use in the treatment of persistent cancer pain SANOFI (FR) 2013-01-16 EP claimed
EP-2545915-A1 2-amino-2-oxoethyl trans-3-[5-(6-methoxy-naphtalen-1-yl)-1,3-dioxan-2-yl]propyl-carbamate for use in the treatment of persistent cancer pain SANOFI (FR) 2013-01-16 EP claimed
US-8119687-B2 Derivatives of dioxan-2-alkyl carbamates, preparation thereof and application thereof in therapeutics SANOFI-AVENTIS (FR) 2012-02-21 US claimed
US-20100280076-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS SANOFI-AVENTIS (FR) 2010-11-04 US claimed
US-20090286868-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS SANOFI-AVENTIS (FR) 2009-11-19 US claimed
EP-1537096-B1 DERIVATIVES OF DIOXANE-2-ALKYL CARBAMATES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2008-09-24 EP claimed
US-20060247290-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS SANOFI-AVENTIS (FR) 2006-11-02 US claimed
US-7119116-B2 Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics SANOFI-AVENTIS (FR) 2006-10-10 US claimed
US-20050182130-A1 Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics SANOFI AVENTIS (FR) 2005-08-18 US claimed
US-12628224-B2 Methods for improved federated machine learning in wireless networks TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) 2026-05-12 US disclosed
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US disclosed
US-12591111-B2 Optical imaging system SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2026-03-31 US disclosed
US-20090286868-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS SANOFI-AVENTIS (FR) 2009-11-19 US disclosed
US-20060247290-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS SANOFI-AVENTIS (FR) 2006-11-02 US disclosed
US-7119116-B2 Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics SANOFI-AVENTIS (FR) 2006-10-10 US disclosed
US-20050182130-A1 Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics SANOFI AVENTIS (FR) 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280076-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS CHRM3, CHRM2, CHRM4 ACACB 829/4885MTNR1A 466/4885MTNR1B 1041/4885
US-20060247290-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS CHRM3, CHRM2, CHRM4 ACACB 829/4885MTNR1A 466/4885MTNR1B 1041/4885
US-20050182130-A1 Derivatives of dioxane-2-alkyl carbamates, preparation thereof and application thereof in therapeutics CHRM3, CHRM2, CHRM4 ACACB 681/4885MTNR1A 540/4885MTNR1B 1234/4885
US-12591111-B2 Optical imaging system VCL, LGALS8, LAGE3 ACACB 4448/4885MTNR1A 3744/4885MTNR1B 4109/4885
US-20090286868-A1 DERIVATIVES OF DIOXAN-2-ALKYL CARBAMATES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS CHRM3, CHRM2, CHRM4 ACACB 829/4885MTNR1A 466/4885MTNR1B 1041/4885
US-20260109732-A1 LIPID AMINES LDLR, NPC1, PHOSPHO1 ACACB 991/4885MTNR1A 520/4885MTNR1B 639/4885
US-12628224-B2 Methods for improved federated machine learning in wireless networks LRRFIP1, RXFP3, RXFP4 ACACB 1500/4885MTNR1A 1696/4885MTNR1B 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.