Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784748 | 0.89 | KDM4E (0.53) | KDM4ENQO1TP53MAPTTSHR | |
| SCHEMBL16959703 | 0.86 | HSD17B10 (0.47) | KDM4ENQO1HIF1APDE4APDE4B | |
| SCHEMBL13634446 | 0.85 | APLNR (0.50) | APLNRKDM4ENQO1HIF1ATAS1R3 | |
| SCHEMBL238087 | 0.85 | APLNR (0.63) | APLNRPDCD1CD274KDM4EPDE4A | |
| SCHEMBL27315198 | 0.83 | MEN1 (0.46) | APLNRKDM4EHIF1ATAS1R3TAS1R1 | |
| SCHEMBL701717 | 0.82 | APLNR (0.47) | APLNRKDM4ENQO1HIF1ATAS1R3 | |
| SCHEMBL19231006 | 0.81 | APLNR (0.44) | APLNRPDCD1CD274TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL2944977 | 0.81 | MELK (0.46) | APLNRKDM4ENQO1HIF1ATAS1R3 | |
| SCHEMBL2016744 | 0.80 | CNR2 (0.46) | APLNRPDCD1CD274PDE4APDE4B | |
| SCHEMBL12637177 | 0.80 | APLNR (0.42) | APLNRPDCD1CD274PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | APLNR 4354/4885PDCD1 4669/4885CD274 4606/4885 |
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | APLNR 4858/4885PDCD1 3315/4885CD274 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.