Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559678 | 0.85 | CYP19A1 (0.43) | NFKB1NFKB2RELACYP19A1CYP3A4 | |
| SCHEMBL17220878 | 0.84 | NFKB1 (0.53) | NFKB1NFKB2RELACYP19A1SMN1; SMN2 | |
| SCHEMBL17227888 | 0.84 | NFKB1 (0.53) | NFKB1NFKB2RELACYP19A1SMN1; SMN2 | |
| SCHEMBL30468827 | 0.81 | NFKB1 (0.53) | NFKB1NFKB2RELACYP19A1SMN1; SMN2 | |
| SCHEMBL25187265 | 0.80 | NFKB1 (0.69) | NFKB1NFKB2RELACYP19A1CYP3A4 | |
| SCHEMBL25264495 | 0.80 | NFKB1 (0.69) | NFKB1NFKB2RELACYP19A1CYP3A4 | |
| SCHEMBL31110640 | 0.77 | NFKB1 (0.43) | NFKB1NFKB2RELACYP19A1MEN1 | |
| SCHEMBL31110641 | 0.77 | NFKB1 (0.43) | NFKB1NFKB2RELACYP19A1MEN1 | |
| SCHEMBL30800496 | 0.77 | NFKB1 (0.43) | NFKB1NFKB2RELACYP19A1MEN1 | |
| SCHEMBL3672681 | 0.72 | CA2 (0.50) | NFKB1NFKB2RELASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951883-B2 | 2H-1-benzopyran derivatives processes for their preparation and pharmaceutical compositions thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2005-10-04 | — | — | US | claimed |