Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002650 | 0.89 | CES2 (0.52) | CES2CES1TSHRALOX15POLB | |
| SCHEMBL38015 | 0.84 | CES1 (0.52) | CES2CES1TSHRALOX15POLB | |
| SCHEMBL22572715 | 0.82 | HTT (0.49) | CES2CES1TSHRPOLBGAA | |
| Acetophenone SCHEMBL25304274 | 0.81 | CES2 (0.68) | CES2CES1TSHRALOX15POLB | |
| SCHEMBL21811153 | 0.81 | CES2 (0.50) | CES2CES1TSHRPOLBL3MBTL1 | |
| SCHEMBL20659172 | 0.79 | HTT (0.50) | TSHRPOLBGAAMAPTMAOB | |
| Acetone SCHEMBL29156010 | 0.79 | SRD5A2 (0.65) | CES2CES1TSHRALOX15L3MBTL1 | |
| SCHEMBL14119103 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15POLB | |
| SCHEMBL9971796 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15POLB | |
| SCHEMBL33953 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655393-A1 | SUBSTITUTED 5-(HET-)ARYLPYRAZOLAMIDES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | Bayer CropScience Aktiengesellschaft (DE) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019016069-A1 | SUBSTITUTED 5-(HET-)ARYLPYRAZOLAMIDES AND SALTS THEREOF AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | WO | disclosed |
| CN-104395289-B | Amide compound and Pesticidal purposes thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |
| US-6844347-B1 | Cyclic guanosine monophosphate modulators; cardiovascular diseases; guanylate cyclase activation | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-01-18 | — | — | US | disclosed |