Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493746 | 0.89 | CES2 (0.60) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL22572715 | 0.82 | HTT (0.49) | CES2CES1TSHRPOLBHTT | |
| SCHEMBL315559 | 0.81 | CES2 (0.52) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL7555313 | 0.79 | TSHR (0.55) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL6448217 | 0.79 | TSHR (0.55) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL20659173 | 0.78 | ALDH1A1 (0.41) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL17187946 | 0.77 | MAPT (0.69) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL7959261 | 0.77 | CES2 (0.48) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL190531 | 0.77 | CES2 (0.50) | CES2CES1LMNATSHRMAPK1 | |
| SCHEMBL75640 | 0.77 | MAPT (0.69) | CES2CES1LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110461834-A | Condensed heterocyclic compouds and composition containing it | SUMITOMO CHEMICAL CO | 2019-11-15 | — | — | CN | disclosed |
| CN-110352192-A | Heterocyclic compound and harmful arthropod control agent containing same | 住友化学株式会社 | 2019-10-18 | — | — | CN | disclosed |
| CN-110023303-A | Tetrazolinone compounds and their use as pest control agents | 住友化学株式会社 | 2019-07-16 | — | — | CN | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-3984379-A | POLYMERIZATION CATALYSTS | TEIJIN LIMITED (JA) | 1976-10-05 | — | — | US | disclosed |