Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006254 | 0.82 | IGLV6-57 (0.34) | — | |
| SCHEMBL1637760 | 0.79 | S100B (0.47) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL16167543 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL3217368 | 0.77 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TERTL3MBTL1TDP1 | |
| SCHEMBL3654511 | 0.76 | S100B (0.44) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL1637260 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL4011698 | 0.76 | DAO (0.31) | — | |
| SCHEMBL11646609 | 0.74 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL28081759 | 0.73 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TERTS100BL3MBTL1 | |
| SCHEMBL27433894 | 0.73 | S100B (0.42) | ALDH1A1CYP3A4TERTS100BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101540-A | USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-07-18 | — | — | US | claimed |
| US-6890934-B2 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-10 | — | — | US | disclosed |
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1136492-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF AS MEDICINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-4119776-A | Vinyl phthalide color formers | NCR CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4026883-A | MACHINE READABLE AND COPIABLE | NCR CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4022771-A | RECORD MATERIALS AND MARKING SYSTEMS | NCR CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4016174-A | USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS | NCR CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171396-A1 | Sulfonamide compounds and uses thereof as medicines | PDE2A, PDE3A, PDE5A | ALDH1A1 476/4885CYP3A4 1384/4885TERT 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.