Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 13/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.40 |
| ▸ | ITGAL | P20701 | 13/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829937 | 0.93 | ITGB2 (0.41) | ITGB2ICAM1ITGALENPP2MAPT | |
| SCHEMBL5830033 | 0.84 | ITGAL (0.47) | ITGB2ICAM1ITGALMAPTL3MBTL1 | |
| SCHEMBL6199421 | 0.81 | ITGAL (0.49) | ITGB2ICAM1ITGALMAPTL3MBTL1 | |
| SCHEMBL5836086 | 0.79 | ITGAL (0.49) | ITGB2ICAM1ITGALENPP2MAPT | |
| SCHEMBL6494072 | 0.79 | ITGAL (0.50) | ITGB2ICAM1ITGAL | |
| SCHEMBL5830184 | 0.79 | ITGAL (0.44) | ITGB2ICAM1ITGALENPP2MAPT | |
| SCHEMBL5830367 | 0.78 | HRH3 (0.39) | ITGB2ICAM1ITGALENPP2L3MBTL1 | |
| SCHEMBL7618990 | 0.78 | ITGAL (0.60) | ITGB2ICAM1ITGALL3MBTL1 | |
| SCHEMBL6198648 | 0.73 | ITGB2 (0.47) | ITGB2ICAM1ITGALMAPTLMNA | |
| SCHEMBL5830284 | 0.73 | OPRM1 (0.51) | ITGB2ICAM1ITGALALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |