Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619602 | 0.93 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL5829944 | 0.93 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL27492722 | 0.83 | ITGAL (0.63) | ITGALITGB2ICAM1 | |
| SCHEMBL5830036 | 0.83 | ITGAL (0.63) | ITGALITGB2ICAM1 | |
| SCHEMBL27474411 | 0.81 | ITGAL (0.60) | ITGALITGB2ICAM1 | |
| SCHEMBL6199429 | 0.81 | ITGAL (0.60) | ITGALITGB2ICAM1 | |
| SCHEMBL6494066 | 0.80 | AKR1C3 (0.40) | — | |
| SCHEMBL7647365 | 0.79 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL5836088 | 0.79 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL6494064 | 0.79 | ITGB2 (0.40) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |