Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829934 | 0.93 | EPHX2 (0.40) | PDE7AALDH1A1LMNAEPHX2MAPT | |
| SCHEMBL5830031 | 0.83 | PDE7A (0.44) | PDE7AALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6494059 | 0.82 | PDE7A (0.36) | PDE7AALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6197862 | 0.80 | PDE7A (0.41) | PDE7AGRM5ALDH1A1LMNAEPHX2 | |
| SCHEMBL6494072 | 0.80 | ITGAL (0.50) | — | |
| SCHEMBL5836083 | 0.79 | ITGAL (0.41) | PDE7AALDH1A1LMNARAB9AHPGD | |
| SCHEMBL5830364 | 0.78 | PDE7A (0.38) | PDE7AALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL5830183 | 0.78 | PDE7A (0.36) | PDE7AALDH1A1LMNARAB9ASPR | |
| SCHEMBL7702269 | 0.77 | ITGB2 (0.48) | PDE7AALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5830812 | 0.75 | SPR (0.42) | PDE7AALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |