Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | GOT1 | P17174 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856946 | 0.85 | C1S (0.38) | C1SKDM4ETP53CYP3A4GOT1 | |
| SCHEMBL29560021 | 0.72 | KDM4E (0.43) | C1SKDM4ETP53CYP3A4GOT1 | |
| SCHEMBL29560277 | 0.71 | KDM4E (0.57) | C1SKDM4ETP53CYP3A4GOT1 | |
| SCHEMBL600018 | 0.71 | KDM4E (0.57) | C1SKDM4ETP53CYP3A4GOT1 | |
| SCHEMBL1996363 | 0.71 | NOS3 (0.53) | MAPT | |
| SCHEMBL6163909 | 0.71 | MAPT (0.30) | MAPTTDP1 | |
| SCHEMBL30493103 | 0.69 | MEN1 (0.41) | C1SKDM4ETP53CYP3A4GOT1 | |
| Hydrochloric Acid SCHEMBL27687770 | 0.69 | KDM4E (0.58) | C1SKDM4ETP53CYP3A4GOT1 | |
| SCHEMBL6162300 | 0.68 | — | — | |
| SCHEMBL80567 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958356-B2 | Guanidine mimics factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-10-25 | — | — | US | disclosed |