Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | MPC2 | O95563 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6495565 | 0.83 | PTPN1 (0.57) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6506168 | 0.81 | PPARD (0.61) | PTPN1PPARG | |
| SCHEMBL14273294 | 0.80 | PTPN1 (0.51) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6232223 | 0.79 | PTPN1 (0.61) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL5031762 | 0.78 | PPARA (0.45) | ALDH1A1PPARG | |
| SCHEMBL6497143 | 0.78 | PTPN1 (0.48) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL6497330 | 0.78 | PTPN1 (0.48) | PTPN1CA2ALDH1A1NPSR1PPARG | |
| SCHEMBL5390735 | 0.77 | FFAR1 (0.56) | ALDH1A1NPSR1PPARGMPC2CYP2C8 | |
| SCHEMBL5031794 | 0.77 | PPARD (0.44) | ALDH1A1PPARG | |
| SCHEMBL14262592 | 0.77 | PTPN1 (0.59) | PTPN1CA2ALDH1A1NPSR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |