Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MPC2 | O95563 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527076 | 0.81 | PPARG (0.49) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6496044 | 0.81 | PTPN1 (0.47) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6530838 | 0.80 | PTPN1 (0.48) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6497143 | 0.80 | PTPN1 (0.48) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6497335 | 0.79 | MEN1 (0.53) | CYP2C9CA2ALDH1A1HPGDNPSR1 | |
| SCHEMBL6506168 | 0.78 | PPARD (0.61) | PTPN1PPARG | |
| SCHEMBL6494429 | 0.78 | PTPN1 (0.53) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6494478 | 0.77 | PTPN1 (0.47) | PTPN1PPARGCYP2C9MPC2CYP2C8 | |
| SCHEMBL6502439 | 0.76 | PPARD (0.61) | PTPN1PPARG | |
| SCHEMBL13524847 | 0.75 | PTPN1 (0.51) | PTPN1PPARGCYP2C9MPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |