Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 10/20 | 0.41 |
| ▸ | MPC2 | O95563 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494478 | 0.86 | PTPN1 (0.47) | PTPN1ALDH1A1NPSR1CA2PPARG | |
| SCHEMBL6496044 | 0.82 | PTPN1 (0.47) | PTPN1ALDH1A1NPSR1CA2MAOA | |
| SCHEMBL6530838 | 0.82 | PTPN1 (0.48) | PTPN1ALDH1A1NPSR1CA2PPARG | |
| SCHEMBL6497330 | 0.80 | PTPN1 (0.48) | PTPN1ALDH1A1NPSR1CA2MAOA | |
| SCHEMBL6527076 | 0.79 | PPARG (0.49) | PTPN1ALDH1A1NPSR1CA2PPARG | |
| SCHEMBL6506168 | 0.78 | PPARD (0.61) | PTPN1PPARGPPARDPPARA | |
| SCHEMBL6494429 | 0.78 | PTPN1 (0.53) | PTPN1ALDH1A1NPSR1CA2MAOA | |
| SCHEMBL13524845 | 0.77 | PTPN1 (0.55) | PTPN1ALDH1A1NPSR1CA2MAOA | |
| Hydrochloric Acid SCHEMBL6495565 | 0.77 | PTPN1 (0.57) | PTPN1ALDH1A1NPSR1CA2MAOA | |
| SCHEMBL6502439 | 0.76 | PPARD (0.61) | PTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |