Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494482 | 1.00 | PPARA (0.54) | PPARAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6503306 | 0.82 | PPARA (0.61) | PPARAACHEMAPTALDH1A1KMT2A | |
| SCHEMBL6495358 | 0.78 | MAPT (0.48) | NPSR1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL6495363 | 0.78 | MAPT (0.48) | NPSR1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL7943968 | 0.76 | PPARA (0.63) | PPARAMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL3944626 | 0.76 | PPARD (0.55) | PPARAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3944624 | 0.76 | PPARD (0.55) | PPARAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3947438 | 0.76 | PPARA (0.84) | PPARAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6236808 | 0.73 | ESRRA (0.60) | PPARAESRRA | |
| SCHEMBL6236807 | 0.73 | ESRRA (0.60) | PPARAESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |