Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943968 | 0.84 | PPARA (0.63) | PPARAKCNJ5KCNJ3CSNK1DKMT2A | |
| SCHEMBL6494482 | 0.82 | PPARA (0.54) | PPARAACHEKCNJ5KCNJ3CSNK1D | |
| SCHEMBL6494480 | 0.82 | PPARA (0.54) | PPARAACHEKCNJ5KCNJ3CSNK1D | |
| SCHEMBL6236807 | 0.81 | ESRRA (0.60) | PPARAHDAC4HDAC8 | |
| SCHEMBL6236808 | 0.81 | ESRRA (0.60) | PPARAHDAC4HDAC8 | |
| SCHEMBL6496067 | 0.81 | KCNJ5 (0.66) | PPARAKCNJ5KCNJ3CSNK1DKMT2A | |
| SCHEMBL6504855 | 0.81 | PPARD (0.65) | PPARAHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3952548 | 0.76 | PPARA (1.00) | PPARAPPARD | |
| SCHEMBL3947438 | 0.75 | PPARA (0.84) | PPARAPPARD | |
| SCHEMBL1581301 | 0.75 | EPHX2 (0.61) | PPARAKMT2ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |