Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.71 |
| ▸ | ALPI | P09923 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | XIAP | P98170 | 1/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | TPH1 | P17752 | 2/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL6494649 | 1.00 | SLC7A5 (0.71) | SLC7A5ALPIPKMPTGS1XIAP | |
| Benzophenone SCHEMBL3857530 | 0.93 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Benzophenone SCHEMBL3857526 | 0.93 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28091935 | 0.93 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL44097 | 0.92 | SLC7A5 (0.72) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL288025 | 0.92 | SLC7A5 (0.72) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL44096 | 0.92 | SLC7A5 (0.72) | SLC7A5ALPIPKMPTGS1XIAP | |
| Terephthalamic Acid SCHEMBL28724671 | 0.87 | SLC7A5 (0.71) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL19295504 | 0.86 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL157002 | 0.86 | SLC7A5 (0.69) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872850-B2 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | MESSAGE PHARMACEUTICALS (US) | 2005-03-29 | — | — | US | disclosed |
| WO-2002083842-A9 | SMALL MOLECULE INHIBITORS OF SECRETION OF PROTEINS ENCODED BY ARE-MRNAS | MESSAGE PHARMACEUTICALS INC (US) | 2004-04-29 | — | — | WO | disclosed |
| US-20030199453-A1 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | S. R. ONE, LIMITED | 2003-10-23 | — | — | US | disclosed |
| WO-2002083842-A2 | SMALL MOLECULE INHIBITORS OF SECRETION OF PROTEINS ENCODED BY ARE-MRNAS | MESSAGE PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199453-A1 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | ASF1A, IGF2BP1, SERBP1 | SLC7A5 778/4885ALPI 3992/4885PKM 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.