Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.72 |
| ▸ | ALPI | P09923 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | XIAP | P98170 | 1/20 | 0.72 |
| ▸ | TPH1 | P17752 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44097 | 1.00 | SLC7A5 (0.72) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL44096 | 1.00 | SLC7A5 (0.72) | SLC7A5PTGS1ALPIPKMXIAP | |
| Benzophenone SCHEMBL3857526 | 0.95 | SLC7A5 (0.81) | SLC7A5PTGS1ALPIPKMXIAP | |
| Benzophenone SCHEMBL3857530 | 0.95 | SLC7A5 (0.81) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL6494649 | 0.92 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| Benzophenone SCHEMBL7628847 | 0.92 | SLC7A5 (0.77) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL6494644 | 0.92 | SLC7A5 (0.71) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL16728148 | 0.88 | SLC7A5 (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL3506064 | 0.88 | SLC7A5 (0.83) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL3506065 | 0.88 | SLC7A5 (0.83) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | claimed |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2022-11-24 | — | — | US | claimed |
| US-9718861-B2 | Potent ligands of the ghrelin receptor | UNIVERSITAET LEIPZIG (DE) | 2017-08-01 | — | — | US | claimed |
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | claimed |
| EP-2462147-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2014-11-12 | — | — | EP | claimed |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-08-09 | — | — | US | claimed |
| US-20080233137-A1 | Compounds that Block the C5a Receptor and Their Use in Therapy | ALLIGATOR BIOSCIENCE AB (SE) | 2008-09-25 | — | — | US | claimed |
| US-7220720-B2 | Melanin-concentrating hormone analogs | MERK & CO., INC. (US) | 2007-05-22 | — | — | US | claimed |
| US-20040254338-A1 | Melanin-concentrating hormone antagonists | MERCK SHARP & DOHME CORP. | 2004-12-16 | — | — | US | claimed |
| EP-1485405-A2 | MELANIN-CONCENTRATING HORMONE ANALOGS | Merck & Co., Inc. (US) | 2004-12-15 | — | — | EP | claimed |
| US-20040147432-A1 | Melanin-concentrating hormone analogs | MERCK SHARP & DOHME CORP. | 2004-07-29 | — | — | US | claimed |
| EP-1416951-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONISTS | Merck & Co., Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| US-20030105278-A1 | Polypeptides for signal transduction; drug screening; dietetics | MERCK SHARP & DOHME CORP. | 2003-06-05 | — | — | US | claimed |
| WO-2003013574-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONISTS | MERCK & CO., INC. (US) | 2003-02-20 | — | — | WO | claimed |
| WO-2003006048-A1 | COMBINATION OF CHIPS (CHEMOTAXIS INHIBITING PROTEIN FROM STAPHYLOCOCCUS AUREUS)-BASED COMPOUNDS | JARI PHARMACEUTICALS B.V. (NL) | 2003-01-23 | — | — | WO | claimed |
| WO-2002097037-A2 | MELANIN-CONCENTRATING HORMONE ANALOGS | MERCK & CO., INC. (US) | 2002-12-05 | — | — | WO | claimed |
| EP-1025127-A1 | MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES | Wapharm AB (SE) | 2000-08-09 | — | — | EP | claimed |
| WO-1998037097-A1 | MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES | WAPHARM AB (SE) | 1998-08-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | SLC7A5 1166/4885PTGS1 2925/4885ALPI 2783/4885 |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | HTR2B, MC1R, HTR1A | SLC7A5 1600/4885PTGS1 109/4885ALPI 2014/4885 |
| US-20040254338-A1 | Melanin-concentrating hormone antagonists | MCHR1, MCHR2, MC1R | SLC7A5 621/4885PTGS1 4075/4885ALPI 4598/4885 |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | SLC7A5 378/4885PTGS1 4428/4885ALPI 2000/4885 |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, NPEPPS, PAM | SLC7A5 1166/4885PTGS1 2925/4885ALPI 2783/4885 |
| US-20030105278-A1 | Polypeptides for signal transduction; drug screening; dietetics | MCHR1, MCHR2, MC4R | SLC7A5 1005/4885PTGS1 2469/4885ALPI 4807/4885 |
| US-20040147432-A1 | Melanin-concentrating hormone analogs | MCHR2, MCHR1, MC1R | SLC7A5 680/4885PTGS1 4274/4885ALPI 4729/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | SLC7A5 64/4885PTGS1 3489/4885ALPI 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.