Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.77 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6493393 | 0.99 | OPRL1 (0.76) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6494781 | 0.96 | OPRL1 (0.84) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6493397 | 0.95 | OPRL1 (0.82) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6486082 | 0.89 | OPRL1 (0.75) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6484553 | 0.89 | OPRL1 (0.75) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6499772 | 0.88 | OPRL1 (0.73) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6483505 | 0.86 | OPRL1 (0.71) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6484351 | 0.85 | OPRL1 (0.70) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6493299 | 0.85 | OPRL1 (0.69) | OPRL1OPRM1OPRK1KCNH2OPRD1 | |
| Hydrochloric Acid SCHEMBL6496887 | 0.85 | OPRL1 (0.69) | OPRL1OPRM1OPRK1KCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044056-A1 | Benzimidazole derivatives | GPR119, OPRL1, INSR | OPRL1 2/4885OPRM1 11/4885OPRK1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.