Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.57 |
| ▸ | SREBF2 | Q12772 | 6/20 | 0.48 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875453 | 0.82 | CDC7 (0.63) | CDC7DBF4SREBF2SREBF1ALDH1A1 | |
| SCHEMBL14736837 | 0.81 | CDC7 (0.56) | CDC7DBF4SREBF2SREBF1PDE10A | |
| SCHEMBL1436189 | 0.77 | CDC7 (0.52) | CDC7DBF4SREBF2SREBF1PDE10A | |
| SCHEMBL27953546 | 0.76 | CDC7 (0.60) | CDC7DBF4SREBF2SREBF1WNT3A | |
| SCHEMBL5232911 | 0.76 | SREBF2 (0.56) | CDC7DBF4SREBF2SREBF1ALDH1A1 | |
| SCHEMBL14736546 | 0.75 | CDC7 (0.49) | CDC7DBF4SREBF2SREBF1PDE10A | |
| SCHEMBL3995172 | 0.74 | RARA (0.60) | CDC7DBF4RARBRARARARG | |
| SCHEMBL28628291 | 0.73 | CDC7 (0.80) | CDC7DBF4ALDH1A1MAPT | |
| SCHEMBL6496395 | 0.73 | PIN1 (0.54) | RARBRARARARGALDH1A1MAPT | |
| SCHEMBL14736938 | 0.73 | CDC7 (0.51) | CDC7DBF4SREBF2SREBF1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |