SCHEMBL649625

SCHEMBL649625

[CH2]COCCOC(C)OCC

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15384196 0.85 LMNA (0.67) LMNATHRB
SCHEMBL248776 0.83 LMNA (0.63) LMNATHRB
SCHEMBL1403987 0.83 LMNA (0.33) LMNA
SCHEMBL651599 0.79
SCHEMBL8065640 0.78
SCHEMBL192032 0.78
SCHEMBL707537 0.78 LMNA (0.71) LMNATHRB
SCHEMBL891598 0.77 LMNA (0.55) LMNATHRB
SCHEMBL16981482 0.77 LMNA (0.55) LMNATHRB
SCHEMBL3453066 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 US claimed
EP-1966129-B1 CARBONATES OF FENICOL ANTIBIOTICS SCHERING PLOUGH LTD (CH) 2011-08-17 EP claimed
EP-1966129-A2 CARBONATES OF FENICOL ANTIBIOTICS Schering-Plough Ltd. (CH) 2008-09-10 EP claimed
WO-2007079010-A2 CARBONATES OF FENICOL ANTIBIOTICS SCHERING-PLOUGH LTD. (CH) 2007-07-12 WO claimed
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS INTERVET INC. 2007-07-05 US claimed
US-8119667-B2 Carbonates of fenicol antibiotics SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) 2012-02-21 US disclosed
EP-1966129-B1 CARBONATES OF FENICOL ANTIBIOTICS SCHERING PLOUGH LTD (CH) 2011-08-17 EP disclosed
EP-1966129-A2 CARBONATES OF FENICOL ANTIBIOTICS Schering-Plough Ltd. (CH) 2008-09-10 EP disclosed
WO-2007079010-A2 CARBONATES OF FENICOL ANTIBIOTICS SCHERING-PLOUGH LTD. (CH) 2007-07-12 WO disclosed
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS INTERVET INC. 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070155799-A1 CARBONATES OF FENICOL ANTIBIOTICS CYP4F3, TET1, CYP4F2 LMNA 2548/4885THRB 2563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.