Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248776 | 0.95 | LMNA (0.63) | LMNAALDH1A1THRBTSHR | |
| Ether SCHEMBL491351 | 0.88 | LMNA (0.80) | LMNAALDH1A1THRB | |
| SCHEMBL3453066 | 0.87 | — | — | |
| Diethylene Glycol Monoethyl Ether SCHEMBL2952919 | 0.86 | ALDH1A1 (0.61) | LMNAALDH1A1THRBTSHR | |
| SCHEMBL15384196 | 0.86 | LMNA (0.67) | LMNATHRB | |
| SCHEMBL10791724 | 0.85 | LMNA (0.57) | LMNAALDH1A1THRBTSHR | |
| SCHEMBL9459 | 0.84 | — | — | |
| SCHEMBL2094168 | 0.84 | LMNA (1.00) | LMNATHRB | |
| SCHEMBL8399199 | 0.82 | LMNA (0.71) | LMNATHRB | |
| SCHEMBL3199752 | 0.81 | LMNA (0.60) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124338-B2 | Use of TDE for isolation of nucleic acids | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110266172-A1 | USE OF TDE FOR ISOLATION OF NUCLEIC ACIDS | ROCHE MOLECULAR SYSTEMS, INC. | 2011-11-03 | — | — | US | disclosed |