Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785770 | 0.83 | SLC6A4 (0.36) | SLC6A4MAOATDP1HSD17B10CYP1A2 | |
| SCHEMBL3781466 | 0.83 | PDE7A (0.37) | SLC6A4MAOA | |
| SCHEMBL12749869 | 0.83 | CYP3A4 (0.43) | SLC6A4MAOANPSR1CYP3A4MAPT | |
| SCHEMBL9515929 | 0.81 | TDP1 (0.45) | TP53DAOAHRHAO1TDP1 | |
| SCHEMBL3786473 | 0.81 | TSHR (0.50) | TP53SLC6A4MAOACYP3A4TSHR | |
| SCHEMBL2652648 | 0.81 | TSHR (0.41) | SLC6A4MAOAHTTNPSR1TSHR | |
| SCHEMBL707892 | 0.81 | ALDH1A1 (0.39) | SLC6A4MAOACYP3A4LMNAMAPT | |
| SCHEMBL29992857 | 0.81 | ALDH1A1 (0.39) | SLC6A4MAOACYP3A4LMNAMAPT | |
| SCHEMBL3723662 | 0.81 | HSD17B10 (0.50) | DAOSLC6A4TDP1HTTIDO1 | |
| SCHEMBL3793113 | 0.81 | TSHR (0.50) | TP53SLC6A4MAOATDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472165-B1 | N-(SUBSTITUTED-PHENYL)-SULFONAMIDE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2023-09-06 | — | — | EP | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |