Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815592 | 0.89 | PNMT (0.47) | TDP1HTTNPSR1DAOAHR | |
| SCHEMBL10410234 | 0.87 | CDK1 (0.45) | TDP1HTTNPSR1DAOAHR | |
| SCHEMBL9040127 | 0.85 | TDP1 (0.40) | TDP1HTTNPSR1DAOAHR | |
| SCHEMBL7531348 | 0.83 | KIF11 (0.42) | TDP1HTTNPSR1DAOHAO1 | |
| SCHEMBL15960057 | 0.83 | THRB (0.48) | TDP1HTTNPSR1DAOMPI | |
| SCHEMBL9696956 | 0.83 | DAO (0.42) | TDP1HTTNPSR1DAOAHR | |
| SCHEMBL10915572 | 0.82 | MPI (0.39) | TDP1HTTNPSR1DAOTP53 | |
| SCHEMBL9478091 | 0.82 | THRB (0.41) | TDP1HTTNPSR1DAOALDH1A1 | |
| SCHEMBL10499652 | 0.82 | HTT (0.39) | TDP1HTTNPSR1DAOTP53 | |
| SCHEMBL6496327 | 0.81 | TP53 (0.44) | TDP1HTTNPSR1DAOAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |