SCHEMBL6496372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6483674	0.85	SMN1; SMN2 (0.48)	PTGDR2SIGMAR1MEN1KMT2ACYP2C19
	SCHEMBL6497414	0.78	HTR2C (0.55)	HTR2AHTR2BHTR2CMEN1MAPT
	Hydrochloric Acid SCHEMBL6484383	0.77	HTR2C (0.54)	HTR2AHTR2BHTR2CMEN1MAPT
	SCHEMBL6485143	0.76	HTR2C (0.46)	PTGDR2HTR2AADRA2AADRA2BADRA2C
	SCHEMBL7030588	0.75	MCL1 (0.52)	HTR2AHTR2CGAAMEN1MAPT
	SCHEMBL7672109	0.74	HTR2C (0.39)	PTGDR2HTR2ACREBBPHTR2CGAA
	SCHEMBL6482946	0.74	PTGDR2 (0.41)	PTGDR2MEN1KMT2ACYP2C9ACHE
	SCHEMBL6491761	0.74	CHRM1 (0.38)	PTGDR2HTR2AADRA2AADRA2BADRA2C
	Diamide SCHEMBL6492807	0.70	PTGDR2 (0.38)	PTGDR2DRD4MEN1KMT2AKDM4E
	SCHEMBL6851523	0.70	HTR2A (0.39)	PTGDR2HTR2AADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.