Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6493920 | 0.81 | PTGDR2 (0.50) | KDM4EHSD17B10CYP1A2LMNAHTR2C | |
| SCHEMBL6485143 | 0.80 | HTR2C (0.46) | MCL1KDM4EHSD17B10CYP1A2LMNA | |
| SCHEMBL3545060 | 0.80 | HTR2C (0.67) | MCL1KDM4EHSD17B10CYP1A2LMNA | |
| SCHEMBL7038582 | 0.80 | HTR2C (0.48) | MCL1KDM4EHSD17B10LMNAHTR2C | |
| SCHEMBL7034581 | 0.80 | PTGDR2 (0.38) | MCL1KDM4EHSD17B10CYP1A2HTR2C | |
| SCHEMBL3550600 | 0.79 | HTR2C (0.68) | MCL1KDM4EHSD17B10CYP1A2LMNA | |
| SCHEMBL6850296 | 0.77 | PDE3B (0.38) | MCL1KDM4EHTR2CHTR2AKMT2A | |
| SCHEMBL5413796 | 0.75 | HTR2C (0.60) | MCL1KDM4EHSD17B10CYP1A2LMNA | |
| SCHEMBL6491761 | 0.75 | CHRM1 (0.38) | MCL1HTR2CHTR2A | |
| SCHEMBL6496372 | 0.75 | PTGDR2 (0.36) | KDM4EHSD17B10CYP1A2HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173440-B1 | TETRACYCLIC AZEPINOINDOLE COMPOUNDS AS 5-HT RECEPTOR LIGANDS | UPJOHN CO (US) | 2004-09-15 | — | — | EP | claimed |