SCHEMBL649682

SCHEMBL649682

ICc1ccc(CI)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CASP1 P29466 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
CYP3A4 P08684 2/20 0.32
GFER P55789 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
IDO1 P14902 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5885407 0.89 ALDH1A1 (0.47) ALDH1A1HPGDALOX15HSD17B10ESR1
SCHEMBL16853360 0.89 GFER (0.47) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL284077 0.86
SCHEMBL3815244 0.83
SCHEMBL687371 0.83
SCHEMBL8388810 0.83
SCHEMBL8226214 0.83
SCHEMBL2724941 0.83
SCHEMBL2666167 0.83 TP53 (0.50) ALDH1A1TSHRTDP1IDO1
SCHEMBL5697082 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037144-A Porphyrin-based super-crosslinked polymer catalyst modified by quaternary phosphonium salt ionic liquid and application thereof 南京工业大学 2026-05-15 CN claimed
CN-118240120-A Poly-gemini imidazolyl ionic liquid shale inhibitor for water-based drilling fluid and preparation method and application thereof 中国石油大学(华东) 2024-06-25 CN claimed
CN-118206774-A Non-fully conjugated metal-supermolecular polymer and preparation method and application thereof 河南大学 2024-06-18 CN claimed
CN-118126283-A Polyurethane composition with stable heat conducting property and preparation method and application thereof 广东普赛达密封粘胶有限公司 2024-06-04 CN claimed
CN-116875998-A Preparation method of electrode loaded with crosslinked cationic polyelectrolyte modified catalyst 南方科技大学 2023-10-13 CN claimed
CN-113773417-B Alpha, alpha' -diiodo-p-xylene, hydroxyl-terminated polyacrylate polyol, polyurethane prepolymer, sealant and preparation method thereof 广东普赛达密封粘胶有限公司 2023-10-13 CN claimed
CN-116284692-A high-Tg hydrocarbon resin, resin composition for high-frequency copper-clad plate and preparation method and application thereof 四川东材科技集团股份有限公司 2023-06-23 CN claimed
CN-114163322-A Ultraviolet absorbent, preparation method and application 中国农业科学院农业环境与可持续发展研究所 2022-03-11 CN claimed
CN-113773417-A Alpha, alpha' -diiodo-p-xylene, hydroxyl-terminated polyacrylate polyol, polyurethane prepolymer, sealant and preparation method thereof 广东普赛达密封粘胶有限公司 2021-12-10 CN claimed
EP-1976888-B1 PROCESS FOR PREPARING A COPOLYMER WITH CONTROLLED ARCHITECTURE, OF TELOMER OR BLOCK COPOLYMER TYPE, OBTAINED FROM VINYL PHOSPHONATE MONOMERS, BY IODINE TRANSFER POLYMERIZATION RHODIA OPERATIONS (FR) 2012-06-13 EP claimed
US-20090306297-A1 PROCESS FOR PREPARING A COPOLYMER WITH CONTROLLED ARCHITECTURE, OF TELOMER OR BLOCK COPOLYMER TYPE, OBTAINED FROM VINYL PHOSPHONATE MONOMERS, BY IODINE TRANSFER POLYMERIZATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-12-10 US claimed
US-4380554-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1983-04-19 US claimed
US-4310657-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1982-01-12 US claimed
US-4016194-A CATALYTIC CARBONYLATION TEXACO INC. (US) 1977-04-05 US claimed
CN-122037144-A Porphyrin-based super-crosslinked polymer catalyst modified by quaternary phosphonium salt ionic liquid and application thereof 南京工业大学 2026-05-15 CN disclosed
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-4380554-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1983-04-19 US disclosed
US-4310657-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1982-01-12 US disclosed
US-3975447-A Preparation of aromatic phosphine oxides by reaction of diarylhalophosphine and benzylic halide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF MLLT1, CRBN, POT1 ALDH1A1 2301/4885HPGD 3074/4885ALOX15 1061/4885
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME PSMA1, PSMB10, RAD51 ALDH1A1 438/4885HPGD 1608/4885ALOX15 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.