Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496854 | 0.96 | OPRL1 (0.59) | OPRL1OPRM1OPRK1CYP1A2CYP2E1 | |
| SCHEMBL6484363 | 0.87 | OPRL1 (0.74) | OPRL1OPRM1OPRK1CYP1A2CYP2E1 | |
| SCHEMBL6484371 | 0.82 | OPRL1 (0.77) | OPRL1OPRM1OPRK1CYP1A2CYP2E1 | |
| Hydrochloric Acid SCHEMBL6494170 | 0.80 | OPRL1 (0.71) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6494058 | 0.78 | OPRL1 (0.59) | OPRL1OPRM1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL6494175 | 0.76 | OPRL1 (0.77) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6493445 | 0.76 | OPRL1 (0.59) | OPRL1OPRM1OPRK1CYP1A2CYP2E1 | |
| Hydrochloric Acid SCHEMBL6494067 | 0.74 | OPRL1 (0.64) | OPRL1OPRM1OPRK1KCNH2 | |
| SCHEMBL6499533 | 0.74 | OPRL1 (0.92) | OPRL1OPRM1OPRK1CYP1A2CYP2E1 | |
| SCHEMBL6483999 | 0.73 | OPRL1 (0.56) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044056-A1 | Benzimidazole derivatives | GPR119, OPRL1, INSR | OPRL1 2/4885OPRM1 11/4885OPRK1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.