Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 10/20 | 0.61 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497480 | 1.00 | ESRRA (0.61) | ESRRAFOXM1CYP3A4PPARDPPARA | |
| SCHEMBL6497642 | 0.89 | ESRRA (0.61) | ESRRAFOXM1CYP3A4PPARDPPARA | |
| SCHEMBL6497637 | 0.89 | ESRRA (0.61) | ESRRAFOXM1CYP3A4PPARDPPARA | |
| SCHEMBL7458048 | 0.84 | ESRRA (0.62) | ESRRAFOXM1CYP3A4PPARDPPARA | |
| SCHEMBL7458053 | 0.84 | ESRRA (0.62) | ESRRAFOXM1CYP3A4PPARDPPARA | |
| SCHEMBL6236807 | 0.84 | ESRRA (0.60) | ESRRAFOXM1CYP3A4PPARAPIM1 | |
| SCHEMBL6236808 | 0.84 | ESRRA (0.60) | ESRRAFOXM1CYP3A4PPARAPIM1 | |
| SCHEMBL6504855 | 0.81 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL6498584 | 0.81 | PIM1 (0.57) | ESRRACYP3A4PIM1PIM2PDE4B | |
| SCHEMBL6235536 | 0.77 | ESRRA (0.60) | ESRRAFOXM1CYP3A4PPARAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |