Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.65 |
| ▸ | PPARA | Q07869 | 11/20 | 0.65 |
| ▸ | PPARG | P37231 | 8/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495372 | 0.86 | PPARD (0.64) | PPARDPPARAPPARGPSEN1PSEN2 | |
| SCHEMBL6497480 | 0.81 | ESRRA (0.61) | PPARDPPARAPPARG | |
| SCHEMBL6497485 | 0.81 | ESRRA (0.61) | PPARDPPARAPPARG | |
| SCHEMBL5974242 | 0.81 | PSEN1 (0.73) | PPARDPPARAPPARGPSEN1PSEN2 | |
| SCHEMBL6503306 | 0.81 | PPARA (0.61) | PPARDPPARAHDAC1HDAC3HDAC2 | |
| SCHEMBL6506444 | 0.80 | HDAC1 (0.73) | PPARDPPARAPPARGHDAC1 | |
| SCHEMBL5796166 | 0.80 | MAPT (0.58) | HDAC1HDAC6 | |
| SCHEMBL5034488 | 0.79 | ALDH1A1 (0.51) | — | |
| SCHEMBL13460784 | 0.77 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL13460817 | 0.76 | PPARD (0.62) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |