Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 17/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502989 | 0.83 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL4827158 | 0.82 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL6505603 | 0.80 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2BMEN1 | |
| SCHEMBL26055757 | 0.78 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2BMEN1 | |
| SCHEMBL6499771 | 0.78 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL6529699 | 0.77 | ADORA1 (0.74) | ADORA1ADORA2AADORA3ADORA2BMEN1 | |
| SCHEMBL6501467 | 0.77 | ADORA1 (1.00) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL26053899 | 0.75 | ADORA1 (0.72) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL26053924 | 0.74 | ADORA1 (0.71) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL24227646 | 0.74 | ADORA1 (0.72) | ADORA1ADORA2AADORA3ADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | claimed |
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | disclosed |