Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820347 | 0.74 | HPGD (0.39) | HPGDPREPCTSDCTSLCTSB | |
| SCHEMBL8737769 | 0.73 | HDAC6 (0.39) | CTSDCTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL510436 | 0.72 | ALDH1A1 (0.42) | HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL60470 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL21707988 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL18097955 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL2077166 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL19852529 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL18432213 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 | |
| SCHEMBL19864899 | 0.72 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |