SCHEMBL649784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27602286	0.90	GRM5 (0.50)	ALDH1A1CYP3A4CYP2C9CYP2C19CA1
	SCHEMBL10057637	0.83	ALDH1A1 (0.55)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL1753231	0.81	ALDH1A1 (0.57)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL1912785	0.80	CYP1A2 (0.50)	ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
	SCHEMBL10172623	0.80	ALDH1A1 (0.52)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL32691488	0.78	ALDH1A1 (0.50)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL9196652	0.78	ALDH1A1 (0.50)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL23399565	0.77	HSD11B1 (0.47)	ALDH1A1CYP2C9CYP2C19GRM5TSHR
	SCHEMBL9204410	0.77	TSHR (0.51)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1
	SCHEMBL9204471	0.77	CYP19A1 (0.51)	ALDH1A1CYP3A4CYP2C9CYP2C19CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.