Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CDK2AP1 | O14519 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509289 | 0.81 | MAPK1 (0.47) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL12507029 | 0.81 | MAPK1 (0.47) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL6505347 | 0.80 | EPHX1 (0.53) | CHRM5CHRM3SIGMAR1SMN1; SMN2NPSR1 | |
| SCHEMBL18629569 | 0.79 | NPSR1 (0.56) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL20758976 | 0.79 | GNAI3 (0.49) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL13460003 | 0.79 | GNAI3 (0.49) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL18956849 | 0.78 | CPN1 (0.46) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 | |
| SCHEMBL16801898 | 0.78 | MAPK1 (0.47) | MAPK1OPRK1CDK2AP1CHEK1SMN1; SMN2 | |
| SCHEMBL2261600 | 0.78 | MAPK1 (0.47) | MAPK1OPRK1CDK2AP1CHEK1SMN1; SMN2 | |
| SCHEMBL12413713 | 0.77 | MAPK1 (0.44) | MAPK1OPRK1CHRM5CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | TRINE PHARMACEUTICALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1389463-A1 | MEDICINE FOR INHIBITING DRUG ELIMINATION PUMP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009843-A1 | Medicine for inhibiting drug elimination pump | ABCB11, ATP6AP1, HRH2 | MAPK1 1239/4885OPRK1 463/4885AHCY 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.