Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720456 | 0.80 | HTT (0.51) | HTTMAPTKMT2AMEN1ABCG2 | |
| SCHEMBL27912191 | 0.76 | HTT (0.44) | HTTMAPTKMT2AMEN1ABCG2 | |
| SCHEMBL6506947 | 0.76 | NPC1 (0.37) | MAPTKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL9660058 | 0.75 | ABCG2 (0.51) | HTTMAPTKMT2AMEN1ABCG2 | |
| Hydrochloric Acid SCHEMBL9098315 | 0.74 | ABCG2 (0.50) | HTTKMT2AMEN1ABCG2PKM | |
| SCHEMBL3750773 | 0.73 | HTT (0.51) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28425962 | 0.73 | HTT (0.44) | HTTMAPTKMT2AMEN1ABCG2 | |
| SCHEMBL6751826 | 0.72 | NPC1 (0.61) | MAPTKMT2AMEN1ABCG2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3318213 | 0.71 | NPC1 (0.60) | MAPTKMT2AMEN1ABCG2ALDH1A1 | |
| SCHEMBL31051680 | 0.69 | ABCG2 (0.60) | KMT2AMEN1ABCG2PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1467971-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | Bayer CropScience AG (DE) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003059887-A1 | SUBSTITUTED PYRAZOLINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107456-A1 | Substituted pyrazolines for use as pesticides | DDT, ACHE, CHRM1 | HTT 4141/4885MAPT 4247/4885KMT2A 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.