Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | ELOC | Q15369 | 1/20 | 0.40 |
| ▸ | ELOB | Q15370 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470635 | 0.71 | VHL (0.46) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL8296391 | 0.69 | VHL (0.44) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL30543398 | 0.64 | VHL (0.54) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL10464 | 0.64 | MAPT (0.46) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL23977277 | 0.62 | VHL (0.44) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL6605520 | 0.62 | VHL (0.51) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL28387239 | 0.62 | VHL (0.44) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL13890187 | 0.62 | VHL (0.51) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL10364205 | 0.59 | VHL (0.62) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL8346491 | 0.59 | VHL (0.41) | VHLELOCELOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |