Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.44 |
| ▸ | ELOC | Q15369 | 1/20 | 0.44 |
| ▸ | ELOB | Q15370 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470635 | 0.71 | VHL (0.46) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL67587 | 0.71 | VHL (0.54) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL30543398 | 0.71 | VHL (0.54) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL28387239 | 0.69 | VHL (0.44) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL6498053 | 0.69 | VHL (0.40) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL6605520 | 0.69 | VHL (0.51) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL13890187 | 0.69 | VHL (0.51) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL6605669 | 0.66 | KDM4E (0.54) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL30543412 | 0.64 | KDM4E (0.41) | VHLELOCELOBKDM4EALDH1A1 | |
| SCHEMBL29222602 | 0.64 | KDM4E (0.41) | VHLELOCELOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |