Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507760 | 1.00 | TSHR (0.46) | TSHRDPP4BPTFALDH1A1KMT2A | |
| SCHEMBL6500416 | 0.88 | EPHX2 (0.37) | TSHRDPP4ALDH1A1KMT2AGAA | |
| SCHEMBL6506039 | 0.83 | MAPT (0.36) | TSHRDPP4ALDH1A1KDM4ECNR2 | |
| SCHEMBL6500205 | 0.83 | DPP9 (0.46) | DPP4ALDH1A1HSD11B1CNR2 | |
| SCHEMBL6500702 | 0.82 | TSHR (0.30) | TSHR | |
| SCHEMBL6510576 | 0.81 | DPP4 (0.52) | DPP4ALDH1A1KMT2AHSD11B1KDM4E | |
| SCHEMBL6387572 | 0.77 | ATM (0.35) | ALDH1A1KMT2AHSD11B1KDM4EGAA | |
| SCHEMBL6426012 | 0.74 | TSHR (0.50) | TSHRDPP4ALDH1A1KMT2AHPGD | |
| SCHEMBL6429260 | 0.74 | TSHR (0.49) | TSHRALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6425891 | 0.74 | TSHR (0.49) | TSHRALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | TSHR 2078/4885DPP4 1365/4885BPTF 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.