Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.45 |
| ▸ | PPARD | Q03181 | 11/20 | 0.45 |
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504835 | 0.86 | PPARG (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6505065 | 0.86 | PPARA (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6528332 | 0.86 | PPARA (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6527212 | 0.86 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL6498088 | 0.85 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL6497351 | 0.85 | POLB (0.43) | PPARAPPARDPPARGALDH1A1HPGD | |
| SCHEMBL6502624 | 0.85 | PPARG (0.46) | PPARAPPARDPPARG | |
| SCHEMBL6502670 | 0.85 | PPARA (0.42) | PPARAPPARDPPARG | |
| SCHEMBL5549055 | 0.85 | PPARA (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6498808 | 0.84 | PPARA (0.44) | PPARAPPARDPPARGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |