Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.43 |
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PPARD | Q03181 | 9/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676301 | 0.94 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6502624 | 0.92 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL6496502 | 0.90 | PPARA (0.39) | PPARGPPARAPPARD | |
| SCHEMBL6497310 | 0.90 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6502884 | 0.89 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6498650 | 0.88 | EPHX2 (0.40) | PPARGPPARAPPARD | |
| SCHEMBL6498320 | 0.86 | PPARA (0.45) | PPARGPPARAPPARD | |
| SCHEMBL7684246 | 0.86 | SHMT1 (0.39) | PPARGPPARAPPARD | |
| SCHEMBL5549055 | 0.86 | PPARA (0.43) | PPARGPPARAPPARDPARP1 | |
| SCHEMBL5552676 | 0.86 | PPARA (0.42) | PPARGPPARAPPARDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |