Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504631 | 0.94 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL6497310 | 0.94 | PPARG (0.54) | PPARGPPARAPPARD | |
| SCHEMBL6495540 | 0.93 | THRB (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6504835 | 0.92 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6505578 | 0.91 | PPARG (0.41) | PPARGPPARAPPARDOPRM1OPRD1 | |
| SCHEMBL6503260 | 0.90 | PPARG (0.47) | PPARGPPARAPPARDOPRM1OPRD1 | |
| SCHEMBL6496860 | 0.88 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL6496051 | 0.87 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL6495781 | 0.86 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL6498650 | 0.86 | EPHX2 (0.40) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |