Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KLK3 | P07288 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507080 | 0.83 | MAPT (0.38) | CETPMAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL5834875 | 0.79 | RIPK1 (0.44) | CETPMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6498366 | 0.72 | MAPT (0.37) | CETPCEPT1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL3631214 | 0.72 | MAPT (0.60) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL5834480 | 0.71 | MAPT (0.42) | CETPMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23609702 | 0.69 | ALDH1A1 (0.54) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL5834492 | 0.68 | APEX1 (0.51) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL25787849 | 0.67 | C1R (0.48) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL31532250 | 0.67 | C1R (0.48) | MAPTALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL6681491 | 0.67 | PDGFRB (0.50) | CETPCEPT1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | OXFORD GLYCOSCIENCE (UK) LTD. (GB) | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203153-A1 | Phthalimide carboxylic acid derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, IDH1 | CETP 4194/4885CEPT1 2136/4885MAPT 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.