Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495893 | 0.92 | PPARA (0.40) | PPARAPPARGALOX5APMCL1DCTPP1 | |
| SCHEMBL6499263 | 0.89 | ALOX5AP (0.41) | PPARAPPARDPPARGALOX5APMCL1 | |
| SCHEMBL6490405 | 0.88 | PPARG (0.48) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6488344 | 0.87 | MCL1 (0.47) | PPARGMCL1 | |
| SCHEMBL6500130 | 0.87 | DCTPP1 (0.47) | PPARGMCL1DCTPP1 | |
| SCHEMBL6497730 | 0.85 | PPARG (0.44) | PPARGMCL1DCTPP1 | |
| SCHEMBL6489066 | 0.84 | PPARG (0.37) | PPARAPPARGALOX5APMCL1DCTPP1 | |
| SCHEMBL6487942 | 0.84 | MCL1 (0.42) | PPARGPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6488196 | 0.83 | PPARG (0.39) | PPARGDCTPP1 | |
| SCHEMBL6496934 | 0.83 | MCL1 (0.54) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PPARA 665/4885PPARD 290/4885PPARG 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.