Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505919 | 0.89 | CCR5 (0.61) | CCR5KCNH2 | |
| SCHEMBL4011565 | 0.87 | CCR5 (0.78) | CCR5KCNH2 | |
| SCHEMBL4011563 | 0.87 | CCR5 (0.78) | CCR5KCNH2 | |
| SCHEMBL4018529 | 0.85 | CCR5 (0.92) | CCR5KCNH2 | |
| SCHEMBL4018532 | 0.85 | CCR5 (0.92) | CCR5KCNH2 | |
| SCHEMBL4015135 | 0.85 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL4015130 | 0.85 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL13719105 | 0.83 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL13967379 | 0.80 | CCR5 (0.70) | CCR5KCNH2 | |
| SCHEMBL13835242 | 0.80 | CCR5 (0.70) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855724-B2 | Tropane derivatives useful in therapy | AGOURON PHARMACEUTICALS, INC. (US) | 2005-02-15 | — | — | US | disclosed |