Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 14/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498378 | 0.89 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL4014899 | 0.88 | CCR5 (0.64) | CCR5KCNH2 | |
| SCHEMBL4014896 | 0.88 | CCR5 (0.64) | CCR5KCNH2 | |
| SCHEMBL4013484 | 0.87 | CCR5 (0.76) | CCR5KCNH2 | |
| SCHEMBL4013479 | 0.87 | CCR5 (0.76) | CCR5KCNH2 | |
| SCHEMBL4012989 | 0.85 | CCR5 (0.83) | CCR5KCNH2 | |
| SCHEMBL4015230 | 0.85 | CCR5 (0.74) | CCR5KCNH2 | |
| SCHEMBL4015226 | 0.85 | CCR5 (0.74) | CCR5KCNH2 | |
| SCHEMBL4012991 | 0.85 | CCR5 (0.83) | CCR5KCNH2 | |
| SCHEMBL13719082 | 0.85 | CCR5 (0.81) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855724-B2 | Tropane derivatives useful in therapy | AGOURON PHARMACEUTICALS, INC. (US) | 2005-02-15 | — | — | US | disclosed |